The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms complications manifestations otitismedia adhesivecapsulitis ankylosingspondylitis benign bph centralretinalartery cholesteatoma crao extraarticular frozenshoulder hyperplasia lupus middleear msk mucocutaneous occlusion
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... : Extension of inflammatory ... pathophysiology #signs ... #symptoms #diagnosis ... #otology
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... becomes more severe Signs ... sensorineural is rare • Mastoiditis ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... with keratotic scaling ... that extend inflammation ... pathophysiology #diagnosis ... #signs #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... hearing loss, mastoiditis ... pathophysiology #diagnosis ... #symptoms #signs
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Non-specific Acute-phase ... • Rate of inflammatory ... etc • Systemic inflammation ... Extra-articular signs ... #symptoms #diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
activation of inflammatory ... Hydronephrosis, Acute ... Pathophysiology #Urology ... #Signs #Symptoms ... #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... trucking" • Acute ... ophthalmology #diagnosis ... #signs #symptoms
Cholesteatoma (of middle ear): Pathogenesis and clinical findings • Congenital trapping of keratinizing epithelium in middle
the middle ear Signs ... Polyp secondary to inflammation ... • Acute otitis ... • Coalescent Mastoiditis ... #diagnosis #complications
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... acute phase reactant ... pathophysiology #diagnosis ... #signs #symptoms
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