The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
Vein Occlusion (CRVO ... CentralRetinalVein #Occlusion #CRVO ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... mutation) that alter inflammatory ... old; F>M Signs/Symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... • Inflammation ... Effusions • Inflammation ... pathophysiology #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... manifestations Skin: • Inflammation ... Eyes: • Globe inflammation ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Psoriatic Arthritis ... • Dactylitis - Inflammation ... Arthritis of DIP ... pathophysiology #diagnosis ... #signs #symptoms
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
Panopthalmitis: inflammation ... Endopthalmitis: inflammation ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
joint disease Inflammatory ... Swollen Joints • Inflammation ... in Rheumatoid arthritis ... mild synovial inflammation ... JointDisease #JointPain #Diagnosis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... reflex) • Orbital inflammation ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... scaling that extend inflammation ... -> Incr local inflammation ... pathophysiology #diagnosis ... #signs #symptoms