The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis complications manifestations acute ankylosingspondylitis benign bph centralretinalartery crao extraarticular frozenshoulder hyperplasia incontinence injury lupus mastoiditis mixed mucocutaneous neurology occlusion
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
scapulothoracic) #AdhesiveCapsulitis ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #signs #stages ... #staging #msk
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... -> Incr local inflammation ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
mucosa leads to inflammation ... : Extension of inflammatory ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Rate of inflammatory ... etc • Systemic inflammation ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Psoriatic Arthritis: Complications • Ocular - Inflammation of middle layer of the eye (the uvea, which
• Ocular - Inflammation ... Valvular disease - Inflammatory ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs ... #symptoms #Complications
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... viscosity and inflammation ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
(neurogenic), inflammation ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
photophobia • GI - Inflammatory ... endoscopy (Not Inflammatory ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms
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