The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... pain (shooting, stabbing ... pathophysiology #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
with keratotic scaling ... hair follicles -> causes ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Symptoms related to complications ... Sores, scars, calluses ... pathophysiology #diagnosis ... #signs #symptoms
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... -> Pathologic fractures ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... Fluoroquinolones - Causes ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology #diagnosis
Obsessive-Compulsive Personality Disorder (OCPD): Pathogenesis and Clinical Findings
 • Miserly - Lack of generosity when it
themselves; hoard in case ... and efficiency, starting ... PersonalityDisorder #Diagnosis ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic