The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... => Fracture propagation ... Stress Fracture ... #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... /Symptoms/Complications ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
prominently in Achilles ... column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis #signs ... #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... AdhesiveCapsulitis #FrozenShoulder ... pathophysiology #diagnosis #symptoms ... #signs #stages ... #staging #msk
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... binge-purge subtype #AnorexiaNervosa ... pathophysiology #diagnosis #signs ... #symptoms #psychiatry
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis #signs ... #symptoms #complications