The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
sweating, trembling, nausea ... carrying anti-anxiety ... Anticipatory Anxiety ... #BehavioralDisorder ... Pathophysiology #diagnosis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... -> AV nicking Stage ... ophthalmology #diagnosis ... #signs #symptoms ... #complications
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging ... #msk
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Symptoms can take ... Gastrointestinal distress (nausea ... Dysphoric mood, anxiety ... Pathophysiology #Diagnosis
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Mental Status Exam ... ideation -> Ex. anxiety ... of illness, the symptoms ... caused by it, and ... #psychiatry #diagnosis
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... of Anxiety: Mind ... flashes, headaches, nausea ... SocialAnxiety #BehavioralDisorder ... Pathophysiology #diagnosis
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
physical fights • Uses ... weapon that can cause ... lengthy period • Stays ... #Conduct #CD #BehavioralDisorder ... Pathophysiology #diagnosis