The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms erythematosus systemic caudaequina classification comparison discherniations fractures gastrointestinal grades grading inflammatory jointdisease jointpain manifestations mucocutaneous musculoskeletal
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Erythematosus #SLE ... #MSK #Musculoskeletal ... #Complications
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Erythematosus #SLE ... Gastrointestinal #Complications
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... C6/7 Aging ->Degeneration ... DiscHerniations #complications ... #msk #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Phenomenon #Lupus ... #SLE #Mucocutaneous ... signs #symptoms #complications
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... Rheumatoid arthritis, Lupus ... ESR, RF, ANA) Degenerative ... #Inflammatory #Degenerative ... Comparison #Versus #MSK
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
• Large lumbar degenerative ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Anterior Sl diastasis ... posterior through Sl ... #Orthopedics #MSK ... #diagnosis #complications
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