The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology orthopedics complications allergic definitions fractures grades hypersensitivity reactions signs sports symptoms types discherniations gustiloanderson hypersensitivityreaction immunology injury lowanklesprain
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Hypersensitivity #Allergy ... #Allergic #Reactions ... #Types #Classification
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... to an allergic ... antigen-surface complex, leading ... immune reaction, leading ... #Types #Classification
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... #Grades #Grading ... #Orthopedics #MSK
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Complications #MSK
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... signs #symptoms #msk
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
-> Mechanical loading ... complications #msk
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
Clinical Findings Classification ... #PCL #Injury #MSK ... pathophysiology #classification
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