The Calgary Guide to Understanding Disease @TheCalgaryGuide
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symptoms diagnosis orthopedics immunology achilles anaphylaxis anterior centralretinalartery chronic closedangle complications crao dislocation glaucoma hypersensitivityreaction hypertensive injury neurology occlusion patellofemoral
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... Sensitization" to Allergen ... Complications: • Acute ... #Immunology #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... symptoms in the acute ... #Anaphylaxis #pathophysiology
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... Patellofemoral #Syndrome #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... Dislocation #Diagnosis #signs ... #symptoms #msk ... #orthopedics #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... Increased pressure gradient ... damage & blindness Signs ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
trucking" • Acute ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
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