The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms complications orthopedics allergy hypersensitivityreaction diabetes fractures grades ophthalmology stages staging syndrome acute adhesivecapsulitis agammaglobulinemia alcoholusedisorder caudaequina cecs
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... Grades #Diagnosis #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... Patellofemoral #Syndrome #pathophysiology ... signs #symptoms #msk
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... Maternal viremia causes ... vessel collapse leading ... > Inflammation causes ... peds #pediatrics #pathophysiology
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
-> Mechanical loading ... complications #msk ... #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #differential #causes ... #pathophysiology
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