The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis symptoms complications endocrinology ophthalmology psychiatry syndrome acute adhesivecapsulitis alcoholusedisorder bulimianervosa caudaequina cecs chronicexertional closedangle compartmentsyndrome diabetic diabeticfoot diabeticketoacidosis
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... pathophysiology #symptoms #signs
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... ischemia -> Venous beading ... retinal ischemia causes ... Neovascularization #Diabetic ... #Retinopathy #Diabetes
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... pathophysiology #diagnosis #signs ... #symptoms #msk
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... out of cells may cause ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... endocrinology #diabetes
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... Glycosylation - AGE cause ... neuropathy => Diabetic ... a person with diabetes ... in inopportune loading
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
autoimmune disorders (diabetes ... a stroke that caused ... diagnosis #symptoms #signs ... stages #staging #msk
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Hyperprolactinemia • Diabetes ... Headaches • Nausea
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
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