The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... pathophysiology #symptoms #signs
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... : -> Shooting, stabbing ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
distractibility - racing ... - Incr risk taking ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... pathophysiology #diagnosis #signs ... #symptoms #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK ... differential #diagnosis #signs
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
- Alcohol craving ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Psychiatry
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
happen at C6/7 Aging ... -> Mechanical loading ... complications #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
autoimmune disorders (diabetes ... diagnosis #symptoms #signs ... #stages #staging ... #msk
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
new activity or taking ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs