The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis symptoms acute alcohol alcoholusedisorder caudaequina closedangle erythematosus glaucoma lupus musculoskeletal ophthalmology pagetsdisease psychiatry sle syndrome systemic withdrawal
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to effects of EtOH ... exacerbated by EtOH ... - Alcohol craving ... , tachycardia, nausea ... Pathophysiology #Diagnosis #Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... diagnosis #symptoms #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• Significant cause ... most frequent cause ... Increased pressure gradient ... damage & blindness Signs ... / Symptoms / Complications
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... pathophysiology #diagnosis #signs ... #symptoms #complications
Alcohol Withdrawal: Clinical Findings and Complications The onset of alcohol withdrawal generally begins 6-24 hours after the
Clinical Findings and Complications ... >2 days after EtOH ... dreams, anorexia, nausea ... Pathophysiology #Diagnosis #Signs ... #Symptoms #EtOH
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