The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
- Alcohol craving ... • Withdrawal symptoms ... , tachycardia, nausea ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Psychiatry
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... onto lateral hip Signs ... /Symptoms/Complications ... FemoralHead #Fractures #msk ... #symptoms #orthopedics
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... post-inflammatory healing ... pathophysiology #diagnosis #symptoms ... #signs #stages ... #staging #msk
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... and Symptoms Associated ... Secrecy surrounding eating ... Sores, scars, calluses ... #symptoms #psychiatry
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
peaking between ... >2 days after EtOH ... dreams, anorexia, nausea ... Pathophysiology #Diagnosis #Signs ... #Symptoms #EtOH
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... bone formation MSK ... -> Conductive hearing ... pathophysiology #diagnosis #signs ... #symptoms #complications