The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis signs orthopedics acute endocrinology fractures psychiatry bulimianervosa classification lupus mnemonic ophthalmology pediatrics peds sle withdrawal 21hydroxylasedeficiency 21ohd achilles
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... tumour causing injury ... Acute #SpinalCord #Injury ... pathophysiology #signs #symptoms ... #msk #orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... lateral hip Signs/Symptoms ... /Complications: ... FemoralHead #Fractures #msk ... pathophysiology #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Clinical Features and Complications ... Typically "inside out" injury ... Fractures #Diagnosis #Complications ... #MSK #Orthopedics
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... diagnosis #signs #symptoms ... #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Findings Compression/injury ... paresthetica • Symptoms ... 3-6 months of symptom ... mass Sensory Symptoms ... MeralgiaParesthetica #MSK
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
cells -> Tissue injury ... Pancarditis and valvular injury ... diagnosis #signs #symptoms ... #complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis #symptoms
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... cause quadriplegia ... hemorrhagic rash; symptoms ... > Inflammation causes ... non-specific viral symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... chromosome 21) Signs / Symptoms ... / Complications ... diagnosis #signs #symptoms
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