The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... tumour causing injury ... Acute #SpinalCord #Injury ... signs #symptoms #msk
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... severe swelling causes ... metabolites induce injury ... > Inflammation causes
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... signs #symptoms #msk
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... the CFL is also injured ... (uncommonly injured ... PTFL is rarely injured ... LowAnkleSprain #Sports #MSK
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Typically "inside out" injury ... Complications #MSK
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... anion gap until it closes ... Abdominal pain, nausea ... pathophysiology #endocrinology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... FemoralHead #Fractures #msk
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... signs #symptoms #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
and release LH causes ... pathophysiology #Ovulation #endocrinology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
possible vascular injury ... - Type 1 or 2 injury ... #Orthopedics #MSK