The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... #Allergic #Reactions ... #Types #Classification
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... tumour causing injury ... Acute #SpinalCord #Injury ... signs #symptoms #msk
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Gustilo-Anderson Classification ... Typically "inside out" injury ... GustiloAnderson #Classification ... Complications #MSK
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... possible vascular injury ... - Type 1 or 2 injury ... PelvicRing #Fractures #Classification ... #Orthopedics #MSK
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions ... #Types #Classification
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... signs #symptoms #msk
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Ligament (PCL) Injury ... Clinical Findings Classification ... PCL: The PCL is injured ... #MSK #Sports #pathophysiology ... #classification
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
most commonly injured ... the CFL is also injured ... (uncommonly injured ... PTFL is rarely injured ... LowAnkleSprain #Sports #MSK
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... FemoralHead #Fractures #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... MeralgiaParesthetica #MSK