The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... causes development ... Allergic reaction ... ivy) #TypeIV #Type4 ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
2.5cm - APC Grade ... 3 - Type 1 or 2 ... #Grading #Orthopedics ... #MSK #diagnosis ... complications #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #orthopedics #diagnosis ... #differential #causes ... #pathophysiology
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
RNA virus that uses ... lymphotropic virus type ... #oncogenesis #pathophysiology ... #immunology #oncology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... #msk #Staging # ... pathophysiology