The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Carpal Tunnel Syndrome: Pathogenesis and clinical findings
 • Dysthesias - Tingling, burning, or painful sensation at
CarpalTunnel #Syndrome #pathophysiology ... #msk #overuse
Overuse Tendinopathy: Pathogenesis and clinical findings
 • Intrinsic factors: Age, Body weight, Nutrition, Gender, Anatomical variations,
Overuse Tendinopathy ... factors: Occupation, Sport ... conditions #Overuse ... #Tendinopathy #pathophysiology ... #msk
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... Tetanus Toxin -> Spores ... lymph -> Koplik's spots ... peds #pediatrics #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #differential #causes ... #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
-> Cotton-wool spots ... retinal ischemia causes ... complications #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk