The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... LowAnkleSprain #Sports ... #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
forces that are wearing ... Larger, weight-bearing ... > Stiffness is short-lived ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
healing (i.e. local ... tissue healing ... pathophysiology #diagnosis ... #symptoms #signs ... stages #staging #msk
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
severe Signs/Symptoms ... (uncommon) • Hearing ... abscess • High grade ... pathophysiology #symptoms ... #signs #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... lateral hip Signs/Symptoms ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... with keratotic scaling ... pathophysiology #diagnosis ... #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
: Extension of inflammatory ... labyrinth): Tinnitus, hearing ... pathophysiology #signs #symptoms ... #diagnosis #otology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... -> Cherry-red spot ... ophthalmology #diagnosis ... #signs #symptoms
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
this process) Inflammatory ... of hematoma -> Inflammatory ... NSAlDs - Block the inflammatory ... #Orthopedics #msk ... pathophysiology #diagnosis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... Secrecy surrounding eating ... Russell's Sign • Sores ... pathophysiology #diagnosis ... #signs #symptoms