The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... most commonly injured ... (uncommonly injured ... PTFL is rarely injured ... LowAnkleSprain #Sports #MSK
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Prolonged shoulder injury ... ligaments First stage ... side) Second Stage ... movement) Third Stage ... #staging #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
happen at C6/7 Aging ... -> Mechanical loading ... complications #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
possible vascular injury ... - Type 1 or 2 injury ... Classification #Grades #Grading ... #Orthopedics #MSK
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Oscillation between mood states ... distractibility - racing ... - Incr risk taking ... maintain this state
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
alterations (result of aging ... Inflammation: Incr tissue injury ... chronic renal injury ... UTIs & bladder stones
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... stability Hard Callus Stage ... #Orthopedics #msk ... #Staging #pathophysiology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
ganglion cell injury ... factors, oxidative injury ... peri-papillary RNFL imaging ... defects => End-stage
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
ganglion cell injury ... factors, oxidative injury ... peri-papillary RNFL imaging ... defects => End-stage