The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Childhood Immunization ... Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... discharge #Childhood
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... diagnosis #signs #symptoms ... #complications
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... • Diagnostic criteria ... diagnosis #signs #symptoms ... #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... diagnosis #signs #symptoms ... #complications
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
>18 years old, criteria ... when arising in childhood ... physical fights • Uses ... weapon that can cause ... signs #psychiatry #criteria
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... vomiting Other • Symptoms ... related to complications ... Russell's Sign • Sores ... , scars, calluses