The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... -> Cotton-wool spots ... #Diabetic #Retinopathy ... ophthalmology #diagnosis ... complications #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive Retinopathy ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #pathophysiology ... ophthalmology #diagnosis
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
focal melting) -> Retinopathy ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
LowAnkleSprain #Sports ... #MSK #orthopedics ... Grading #Grades #Diagnosis ... #pathophysiology
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral #Syndrome #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Complications #pathophysiology ... signs #symptoms #diagnosis
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
Spondylolisthesis #MSK ... #diagnosis #pathophysiology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
CubitalTunnel #Syndrome #Diagnosis ... #pathophysiology ... signs #symptoms #msk
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Femur #Fractures #msk ... #orthopedics #diagnosis ... #differential # ... causes #pathophysiology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... MeralgiaParesthetica #MSK ... #pathophysiology ... #differential # ... diagnosis #signs