The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... /Symptoms/Complications ... #symptoms #pathophysiology ... #msk #orthopedics
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... auto-reactive B and CD ... , Carditis #Acute ... pathophysiology #diagnosis #signs ... #symptoms #complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... vasoconstrictive • Acute ... -> AV nicking Stage ... ophthalmology #diagnosis #signs ... #symptoms #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... lights are a key symptom ... damage & blindness Signs ... / Symptoms / Complications ... Photophobia #Acute
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder (CD ... >18 years old, criteria ... lengthy period • Stays ... #signs #psychiatry ... #criteria
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... pathophysiology #diagnosis #signs ... #symptoms #complications