The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Biomechanical Factors • Contact ... / Symptoms / Complications ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
damage & blindness Signs ... / Symptoms / Complications ... scotomas of various shapes ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder ... lengthy period • Stays ... #CD #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... #diagnosis #signs
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
to progress to conduct ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry #criteria