The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms sle adhesivecapsulitis boutonniere caudaequina comparison deformity degenerative differential diffuse discherniations dupuytrens erythematosus frozenshoulder inflammatory jointdisease jointpain lfcn
Spondylosis - Pathogenesis and Complications Vertebral disease that may compress the vertebral canal from all sides Note: Do
Pathogenesis and Complications ... Vertebral disease ... #Spondylosis #pathophysiology ... #msk #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Phenomenon #Lupus ... Manifestations #pathophysiology ... signs #symptoms #complications
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... happen at C6/7 Aging ... DiscHerniations #complications ... #msk #pathophysiology
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
intervertebral disc disease ... Tingling, Burning, Stinging ... , Stabbing) - ... MeralgiaParesthetica #MSK ... #pathophysiology
Boutonniere Deformity: Pathogenesis and Complications • Hyperextension of DIP • Flexion of PIP => Boutonniere Deformity =>
Pathogenesis and Complications ... joint => Premanent contracture ... Boutonniere #Deformity #pathophysiology ... #msk #rheumatoidarthritis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Dupuytren’s Disease: Pathogenesis and Clinical Findings • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
Dupuytren’s Disease ... Clinical Findings • Aging ... #Contractures # ... pathophysiology ... #msk
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... FrozenShoulder #pathophysiology ... signs #stages #staging ... #msk
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