The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms adhesivecapsulitis boutonniere caudaequina deformity diffuse discherniations disease disruptors dupuytrens fracture frozenshoulder healing orthopedics pagetsdisease rheumatoidarthritis scleroderma syndrome
Disc Herniations - Pathogenesis and Complications • 90% of Lumbar disc herniations happen at L4/5 and L5/S1 •
Pathogenesis and Complications ... happen at C6/7 Aging ... DiscHerniations #complications ... #msk #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
ligaments First stage ... side) Second Stage ... movement) Third Stage ... FrozenShoulder #pathophysiology ... #staging #msk
Boutonniere Deformity: Pathogenesis and Complications • Hyperextension of DIP • Flexion of PIP => Boutonniere Deformity =>
Pathogenesis and Complications ... joint => Premanent contracture ... Boutonniere #Deformity #pathophysiology ... #msk #rheumatoidarthritis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Dupuytren’s Disease: Pathogenesis and Clinical Findings • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
Clinical Findings • Aging ... Dupuytrens #Disease #Contractures ... #pathophysiology ... #msk
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Renal Failure - Mask ... (i.e. a "purse-string ... Finger/hand/elbow contractures ... #Scleroderma #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... stability Hard Callus Stage ... #Orthopedics #msk ... #Staging #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology ... signs #symptoms #complications
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