The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs complications stages adhesivecapsulitis caudaequina disruptors extraarticular fracture frozenshoulder gait healing lupus manifestations mucocutaneous orthopedics pagetsdisease rheumatoidarthritis sle
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis (RA ... blood vessels (vasculitis ... effusion on CXR • RA ... inflammation tends to cause ... pathophysiology #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
exposed areas -> Scaring ... with keratotic scaling ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... diagnosis #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... a stroke that caused ... pathophysiology #diagnosis #symptoms ... signs #stages #staging ... #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... -> Pathologic fractures ... Skull expansion causes ... diagnosis #signs #symptoms
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology
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