The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Vasculitis -> Acute ... - Budd Chiari Syndrome ... Gastrointestinal #Complications ... signs #symptoms #diagnosis
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... • Ex: Systemic Lupus ... Erythematosus, ... Stevens-Johnson Syndrome ... Classification #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Erythematosus ... #SLE #MSK #Musculoskeletal ... #Complications ... signs #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... Sjögren's, the syndrome ... RA) or systemic lupus ... erythematosus ( ... Pathophysiology #Diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to known allergen ... symptoms in the acute ... Signs / Symptoms / Complications ... pathophysiology #immunology #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Anterior Cord Syndrome ... weakness and #Acute ... #diagnosis #pathophysiology ... signs #symptoms #msk
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Signs / Symptoms / Complications ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #diagnosis #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... TendonRupture #diagnosis ... pathophysiology #msk