The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
Aqueous Humor Production ... structural integrity of ocular ... #AqueousHumor #Production ... #Drainage #flow ... Pathophysiology #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... reduces blood flow ... Amsler grid) - Macular ... early disease) #AgeRelated ... pathophysiology #ophthalmology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... with reduced tear production ... pathophysiology #ophthalmology
Retinitis Pigmentosa: Pathogenesis and Ocular Manifestations
 • Inherited mutation of rhodopsin gene -> Mode of inheritance
Pathogenesis and Ocular ... photoreceptor protein production ... formation • Macular ... atrophy • Cystoid macular ... pathophysiology #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
-> crowding of ocular ... resistance to the flow ... pathophysiology #ophthalmology
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Manifestations • Ocular ... phase reactant production ... lung fibrosis #AnkylosingSpondylitis
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
intra- or peri-ocular ... Altered myocilin production ... Decr axoplasmic flow ... pathophysiology #ophthalmology