The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Onchocerciasis “River Blindness”: Pathogenesis and Ocular Manifestations
Vectorial Transmission
-> Onchocerca volvulus, a parasitic helminth, matures in to
Pathogenesis and Ocular ... Manifestations ... RiverBlindness #pathophysiology ... #ophthalmology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... Amsler grid) - Macular ... early disease) #AgeRelated ... MacularDegeneration #pathophysiology ... #ophthalmology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular ... Manifestations ... #Xeropthalmia #pathophysiology ... #ophthalmology
Retinitis Pigmentosa: Pathogenesis and Ocular Manifestations
 • Inherited mutation of rhodopsin gene -> Mode of inheritance
Pathogenesis and Ocular ... Manifestations ... formation • Macular ... RetinitisPigmentosa #pathophysiology ... #ophthalmology
Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
Production and Drainage ... structural integrity of ocular ... AqueousHumor #Production #Drainage ... #flow #Pathophysiology ... #ophthalmology
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... • Ocular - Inflammation ... lung fibrosis #AnkylosingSpondylitis ... Extraarticular #Manifestations ... Complications #pathophysiology