The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis msk classification allergy complications signs symptoms acute causes compartmentsyndrome definitions differential disruptors femoralhead femur fracture grades grading gustiloanderson
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... as potentially ... lgE Abs persist
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... => Fracture propagation ... loading Stress Fracture ... StressFractures #msk #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... bilateral rami fractures ... Grade 2 - Rami fracture ... #PelvicRing #Fractures ... Grades #Grading #Orthopedics
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Open Fractures: ... Mechanisms, Clinical Features ... Classification #Open #Fractures ... Complications #MSK #Orthopedics
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... Subtrochanteric #Femur #Fractures ... #msk #orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... signs #symptoms #orthopedics
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
bleeding tendency/fracture ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Plasma Cells -> lgE Abs ... Tissue edema #Allergic
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Production of lgE Abs ... leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... chondrocytes at fracture ... > bridging the fracture ... #Stages #Orthopedics
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