The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Clinical Features and Complications ... Typically "inside out ... Fractures #Diagnosis #Complications ... #MSK #Orthopedics
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Gout: Pathogenesis ... Medications (ASA, ACE ... Chronic tophaceous gout ... Pathophysiology #Complications ... #Gout #Tophaceous
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... renal tubules - ACE-inhibitors ... Pathophysiology #Complications ... #Gout
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... pathophysiology #msk #orthopedics
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... Signs / Symptoms / Complications ... Photophobia #Acute
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL