The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis msk symptoms injury mechanisms pharmacology psychiatry sideeffects achilles acs anterior anteriorcruciateligament chondrocalcinosis closedangle compartmentsyndrome cppd disease dislocation firstgeneration
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute ... restlessness #AntiPsychotics
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Second Generation Antipsychotics ... Antagonism - Block ACh ... Gut, mouth, eyes ... Mechanism unknown #AntiPsychotics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... pathophysiology #msk #orthopedics
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... Dislocation #Diagnosis #signs ... symptoms #msk #orthopedics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... pathophysiology #signs ... symptoms #msk #orthopedics
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... damage & blindness Signs ... Photophobia #Acute
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings • Feeling a "pop" • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Disease - Acute ... to crystals -> Acute ... ) (tends to be out ... CPPD #Disease #Signs
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