The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
- Alcohol craving ... • Withdrawal symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Block action of ACh ... Extrapyramidal Symptoms ... bradykinesia/akinesia • Acute ... #pharmacology #diagnosis ... #psychiatry
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
distractibility - racing ... MoodDisorders #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Psychiatry
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... lights are a key symptom ... bodies, shallow ACD ... Increased pressure gradient ... Photophobia #Acute
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Injury #Syndromes #diagnosis ... pathophysiology #signs #symptoms ... #msk #orthopedics
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Judgement - Ability to act ... of illness, the symptoms ... MentalStatusExam #MSE #psychiatry ... #diagnosis #evaluation
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
mortality rates of all ... psychiatric illnesses ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry