The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... damaged BRB appears as ... -> Cotton-wool Spots ... -> Elschnig's Spots ... signs #symptoms #complications
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... pathophysiology #msk #orthopedics
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Medications (ASA, ACE ... joint space -> Chronic ... Pathophysiology #Complications
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... limbs caused by chronic ... bradykinesia/akinesia • Acute
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
recognizes allergen as ... Allergen-specific lgE Abs ... cells recruited Complications ... : • Acute Asthma
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... bodies, shallow ACD ... Signs / Symptoms / Complications ... Photophobia #Acute
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... AnteriorCruciateLigament #ACL ... #Injury #MSK #Sports
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
Signs / Symptoms / Complications ... inflammation • Acute ... Mastoiditis • Chronic ... signs #diagnosis #complications
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
gum disease from chronic ... indication of chronic ... Symptoms related to complications ... , such as frequent ... Russell's Sign • Sores