The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... Pathophysiology #Pharmacology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #differential #causes
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Dizziness - Nausea ... Pathophysiology #Pharmacology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Systemic effect -> Nausea ... Pathophysiology #Psychiatry #Pharmacology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
their turn • Causes ... signs #psychiatry #criteria
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
, and/or limbs caused ... #SideEffects #pharmacology
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... • Diagnostic criteria
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
>18 years old, criteria ... physical fights • Uses ... weapon that can cause ... signs #psychiatry #criteria
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... Healing #Stages #Orthopedics
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... Serotonin Toxicity Criteria