The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology msk complications fractures allergy definitions grades hypersensitivity reactions types alcoholusedisorder diabetes diabetic differential disruptors etoh femur fracture gustiloanderson healing
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... causes development ... #Types #Classification ... #Diagnosis #Definitions
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Gustilo-Anderson Classification ... GustiloAnderson #Classification ... Open #Fractures #Diagnosis ... Complications #MSK #Orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... #Grades #Grading ... #Orthopedics #MSK ... #diagnosis #complications
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
ischemia -> Venous beading ... retinal ischemia causes ... ophthalmology #diagnosis
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
- Alcohol craving ... , tachycardia, nausea ... Pathophysiology #Diagnosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... pathophysiology #diagnosis
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