The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #differential #causes ... #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
their turn • Causes ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
to produce all classes ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
sweating, trembling, nausea ... PanicDisorder #Anxiety #BehavioralDisorder ... #Pathophysiology
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
RNA virus that uses ... #oncogenesis #pathophysiology ... #immunology #oncology
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Disorder (SAD) - Pathophysiology ... flashes, headaches, nausea ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
physical fights • Uses ... weapon that can cause ... #Conduct #CD #BehavioralDisorder ... #Pathophysiology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fluoroquinolones - Causes ... Healing #Stages #Orthopedics ... #msk #Staging #pathophysiology