The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs psychiatry pharmacology inhibitors msk achilles antipsychotics bulimianervosa chronic femoralhead firstgeneration hypertensive mechanisms ophthalmology opiate opioid pagetsdisease retinopathy serotoninnorepinephrine
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Selective Serotonin ... Dizziness - Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... , Vomiting Serotonin ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
lateral hip Signs/Symptoms ... /Complications: ... #msk #diagnosis ... pathophysiology #signs #symptoms ... #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... /Complications: ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... ophthalmology #diagnosis ... #signs #symptoms ... #complications
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Extrapyramidal Symptoms ... , and/or limbs caused ... bradykinesia/akinesia • Acute ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... are more acute ... The less acute behavioral ... Gastrointestinal distress (nausea ... Pathophysiology #Diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... -> Pathologic fractures ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... related to complications ... Sores, scars, calluses ... pathophysiology #diagnosis ... #signs #symptoms
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... make a clinical diagnosis ... following clinical features ... Pathophysiology #Psychiatry #Diagnosis ... #Signs #Symptoms
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