The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs complications msk sle acquired avascularnecrosis bulimianervosa disorders erythematosus femur fractures manifestations mucocutaneous musculoskeletal psychiatry sedondary subtrochanteric systemic
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Normal CK • Osteoporosis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Acquired Disorders of Reduced Bone Strength: Pathogenesis • Hyperparathyroidism • Vitamin D deficiency • Malabsorption syndromes
Diabetes • Other causes ... Acquired #Disorders #BoneStrength ... #pathophysiology ... #differential # ... diagnosis #osteoporosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... young people) • Osteoporosis ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
) • Multiple causes ... therapy - Lupus ... AvascularNecrosis #pathophysiology ... #diagnosis #signs ... #symptoms
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
hormone levels cause ... -> Osteopenia/Osteoporosis ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
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