The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology signs complications msk ophthalmology psychiatry sle staging acute adhesivecapsulitis alcohol aseptic avascularnecrosis behavioraldisorder cd centralretinalartery chronic closedangle conduct
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... pathophysiology #signs #symptoms
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... Inflammatory Stage ... ) • Fracture disrupts ... Fluoroquinolones - Causes ... #Orthopedics #msk
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... Phenomenon #Lupus ... diagnosis #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
Hypertension Stage ... vascular tortuosity Stage ... -> AV nicking Stage ... Cotton-wool Spots Stage ... diagnosis #signs #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... side) Second Stage ... movement) Third Stage ... pathophysiology #diagnosis #symptoms ... #signs #stages
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
hypercoagulable state ... causing localized stasis ... Hypercoagulable state ... retinal edema caused ... diagnosis #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... are connected) Stage ... mastoid air cells) Stage ... hearing loss, nausea ... pathophysiology #signs #symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
lights are a key symptom ... • Significant cause ... most frequent cause ... blindness Signs / Symptoms ... scotomas of various shapes
Mental Status Exam (MSE) Note: The MSE is a "snapshot" of a patient at a specific time. You
Mental Status Exam ... clothing, appears stated ... of illness, the symptoms ... caused by it, and
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... Nephrolithiasis (Kidney Stones ... Skull expansion causes ... middle ear bones causes ... diagnosis #signs #symptoms
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