The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... => Microscopic fractures ... => Fracture propagation ... loading Stress Fracture ... StressFractures #msk #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Sacral compression fracture ... Grade 2 - Rami fracture ... posterior ilium fracture ... Grades #Grading #Orthopedics
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: ... Mechanisms, Clinical Features ... Classification #Open #Fractures ... Complications #MSK #Orthopedics
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... Subtrochanteric #Femur #Fractures ... #msk #orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... signs #symptoms #orthopedics
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... (and disruptors ... disrupts local ... #Stages #Orthopedics ... pathophysiology #diagnosis #disruptors
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
bleeding tendency/fracture ... pathophysiology #orthopedics
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Neurobiology: disruptions ... athletics) #AnorexiaNervosa
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
increased risk of fracture ... warmth) GENERAL FEATURES ... binge-purge subtype #AnorexiaNervosa
Anorexia Nervosa: Signs and Symptoms
Binge/Purge Subtype - Recurrent (once per week) episodes of binge-eating or purging,
psychological/behavioral features ... irritability #AnorexiaNervosa