The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis msk signs symptoms immunology anaphylaxis injury achilles acl allergic anterior anteriorcruciateligament closedangle compartmentsyndrome dislocation fracture glaucoma healing hypersensitivityreaction management
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... as potentially ... lgE Abs persist ... Complications: • Acute ... #Immunology #pathophysiology
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... #pathophysiology ... #orthopedics
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Plasma Cells -> lgE Abs ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... symptoms in the acute ... #Anaphylaxis #pathophysiology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... symptoms #msk #orthopedics ... #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... signs #symptoms #pathophysiology ... #msk #orthopedics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... Syndromes #diagnosis #pathophysiology ... symptoms #msk #orthopedics
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments (Acute ... should be provided, as ... well as allergy ... Treatments #Management #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... bodies, shallow ACD ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing (and disruptors ... ) • Fracture disrupts ... Healing #Stages #Orthopedics ... #msk #Staging #pathophysiology ... #diagnosis #disruptors
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