The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk signs symptoms anorexianervosa complications acs acute causes classification compartmentsyndrome femoralhead femur genetics grading healing pediatrics peds pelvicring praderwilli
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Sacral compression fracture ... 2 - Rami fracture ... #PelvicRing #Fractures ... #Grading #Orthopedics
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... => Microscopic fractures ... => Fracture propagation ... loading Stress Fracture ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Atypical femur fracture ... Subtrochanteric #Femur #Fractures ... #msk #orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... chondrocytes at fracture ... #Stages #Orthopedics ... #msk #Staging #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
bleeding tendency/fracture ... CompartmentSyndrome #ACS #pathophysiology ... #orthopedics
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
increased risk of fracture ... highest mortality rates ... of all psychiatric ... Complications #pathophysiology ... signs #symptoms #psychiatry
Anorexia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: concordance
Genetics: concordance rates ... Neurobiology: disruptions ... AnorexiaNervosa #pathophysiology ... signs #symptoms #psychiatry
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