The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics ... #pathophysiology
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
metabolic demand of growing ... branching of vessels leading ... #Prematurity #peds ... #pediatrics #pathophysiology ... #ophthalmology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification #Grades #Grading ... #Orthopedics #MSK ... complications #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
ischemia -> Venous beading ... Retinopathy #Diabetes #ophthalmology ... complications #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Increased pressure gradient ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
vessel collapse leading ... #Immunization #peds ... #pediatrics #pathophysiology