The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms gh orthopedics acs anterior compartmentsyndrome dislocation feedbackloop hyperthyroidism msk overproduction pituitary primary ra rheumatoidarthritis shoulder
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... share the same pathophysiology ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipid • GH excess ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Hyperthyroidism #endocrinology ... #pathophysiology
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... disperse. => Excess ... compartment pressure #Acute ... CompartmentSyndrome #ACS #pathophysiology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
joint => Force exceeds ... to glenoid -> Acute ... #orthopedics #pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Non-specific Acute-phase ... joint capsule exceeds ... RheumatoidArthritis #RA #pathophysiology
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