The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pediatrics erythematosus genetics systemic 21hydroxylasedeficiency 21ohd diabeticketoacidosis dka gastrointestinal glftap macroadenoma manifestations masseffects mnemonic msk mucocutaneous musculoskeletal otitismedia pituitary
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... #SLE #Mucocutaneous ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Obesity -> Type 2 diabetes ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
Immunocompromised, Diabetes ... lower tract: As a complication ... bacteriuria or cystitis (see ... UrinaryTractInfection #UUTI #Pathophysiology ... #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... seizures, abscess (see ... #OtitisMedia #pathophysiology ... #diagnosis #symptoms ... #signs #peds #pediatrics
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms ... / Complications ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
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