The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... Signs/Symptoms/Complications ... #msk #diagnosis ... #pathophysiology ... signs #symptoms #orthopedics
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
Retinopathy of Prematurity ... -> Neovascular complications ... branching of vessels leading ... #Prematurity #peds ... #pediatrics #pathophysiology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... #Fracture #Healing ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... -> Conductive hearing ... PagetsDisease #pathophysiology