The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Anterior Sl diastasis ... #Grading #Orthopedics ... MSK #diagnosis #complications ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... abscess • High grade ... Otalgia (Ear Pain) fades ... Balance Problems #Acute ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... hypothalamus =>Prader-Willi ... Signs/Symptoms/Complications ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... Signs/Symptoms/Complications ... signs #symptoms #pathophysiology ... #msk #orthopedics
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... resolve by 72 hours Complications ... seizures, abscess (see ... #OtitisMedia #pathophysiology ... symptoms #signs #peds
Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
metabolic demand of growing ... -> Neovascular complications ... branching of vessels leading ... #Prematurity #peds ... #pediatrics #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... cells recruited Complications ... : • Acute Asthma ... Allergy #Immunology #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... Increased pressure gradient ... Signs / Symptoms / Complications ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology